Four young girls have mysteriously disappeared in Seattle within a brief span of time, sparking fears of a potential serial killer in the city. The FBI's specialized unit, dedicated to analyzing criminal behavior, has taken on the case. Led by Jason Gideon, the team works to create a psychological profile of the suspect by visiting crime scenes, interviewing witnesses, and delving into the criminal's psyche. Jason is not one to frequent the FBI's forensic labs, preferring to focus on the human element of the investigation.