During the 19th century in Dublin and New York, the brewing empire of the wealthy Guinness family is prospering. After the death of the patriarch, Benjamin Guinness, who played a key role in the business's success, his four grown children - Arthur, Edward, Ann, and Ben - are left to carry on the company's tradition. Despite his passing, their father's formidable influence persists, causing a series of interconnected tragedies among the heirs.